李昭廷

助理教授

学士/硕士/博士（中国药科大学）

李昭廷博士现任香港中文大学（深圳）医学院助理教授（课题组组长/PI），博士生导师。李昭廷博士本硕博毕业于中国药科大学，之后赴美国威斯康星大学麦迪逊分校药学院完成博士后训练。研究方向主要集中于细胞治疗，生物制剂，药物递送，和免疫治疗。近五年以第一或通讯作者身份在PNAS, Nature Communications, Science Advances, Chemical Society Reviews, Advanced Materials, Advanced Functional Materials, Advanced Drug Delivery Reviews, Journal of Controlled Release等杂志发表SCI论文十余篇，研究被Nature Reviews Materials, Chemical Society Reviews等杂志报道引用, 并入选Nature Communications Editors’ Highlights。李昭廷博士担任Asian Journal of Pharmaceutical Sciences和 Nano Materials Science杂志青年编委及 Frontiers in Bioengineering and Biotechnology 客座编辑等。

代表作

1. Z. Li, F. Mo, Y. Wang, W. Li, Y. Chen, J. Liu, Ting-Jing Chen-Mayfield, Q. Hu, Enhancing Gasdermin-Induced Tumor Pyroptosis Through Preventing ESCRT-Dependent Cell Membrane Repair Augments Anti-Tumor Immune Response, Nature Communications, 13, 6321, 2022.

2. Z. Li, Y. Ding, J. Liu, J. Wang, F. Mo, Y. Wang, P. Sondel, S. Hong, Q. Hu, Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment, Nature Communications, 13, 1845, 2022.

3. Z. Li, L. Zhu, H. Sun, Y. Shen, D. Hu, W. Wu, Y. Wang, C. Qian, M. Sun, Fluorine assembly nanocluster breaks the shackles of immunosuppression to turn the cold tumor hot, PNAS, vol. 117 no. 49, 2020.

4. Z. Li, Y. Wang, Y. Shen, C. Qian, D. Oupicky, M. Sun, Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti-PD-L1 immunotherapy, Science Advances, eaaz9240, 2020.

5. Y. Wang#, Z. Li#, F. Mo, T. Mayfield, A. Sainia, A. LaMerea, Q. Hu, Chemically Engineering Cells for Precision Medicine, Chemical Society Reviews, 2023, 52, 1068-1102. Co-first author.

6. Z. Li, Y. Wang, J. Liu, P. Rawding, J. Bu, S. Hong, Q. Hu, Chemically and Biologically Engineered Bacteria-Based Delivery Systems for Emerging Diagnosis and Advanced Therapy, Advanced Materials, 33(38), 2021, e2102580.

7. Y. Ding#, Z. Li#, A. Jaklenec, Q. Hu, Vaccine delivery systems toward lymph nodes, Advanced Drug Delivery Reviews, 2021 Dec:179:113914. Co-first author.

8. Z. Li, Y. Wang, Y. Ding, L. Repp, G. Kwon, Q. Hu, Cell-Based Delivery Systems: Emerging Carriers for Immunotherapy, Advanced Functional Materials, 31 (23), 2021.

9. L. Zhu#, Z. Li#, N. Liu, H.H. Sun, Y.X. Wang, M.J. Sun, Dynamically Deformable Protein Delivery Strategy Disassembles Neutrophil Extracellular Traps to Prevent Liver Metastasis, Advanced Functional Materials, 31, 2021. Co-first author.

10. Z. Li, Y. Deng, C. Tan, H. Sun, H. Li, F. Mo, Y. Wang, J. Li, Z. Zhou, M. Sun, Redox modulation with a perfluorocarbon nanoparticle to reverse Treg-mediated immunosuppression and enhance anti-tumor immunity, Journal of Controlled Release, 2023 Jun:358:579-590.