多个表达矩阵文件合并

2024-05-30 14:49| 来源: 网络整理| 查看: 265

今天群主给了我们学徒一个任务，下载数据集：https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE84073

我想看到，HCC，CHC，CC这3组，跟healthy的分开比较，然后出3个火山图，3个热图。那么首先需要下载counts值矩阵，样本信息如下：

GSM2653819 Healthy1-Tissue_1 [RNA-Seq] GSM2653820 Healthy1-Tissue_2 [RNA-Seq] GSM2653821 Healthy2-Tissue [RNA-Seq] GSM2653822 Healthy3-Tissue [RNA-Seq] GSM2653823 HCC1-Tissue_1 [RNA-Seq] GSM2653824 HCC1-Tissue_2 [RNA-Seq] GSM2653825 HCC3-Tissue [RNA-Seq] GSM2653826 CHC1-Tissue_1 [RNA-Seq] GSM2653827 CHC1-Tissue_2 [RNA-Seq] GSM2653828 CHC2-Tissue [RNA-Seq] GSM2653829 CC1-Tissue_1 [RNA-Seq] GSM2653830 CC1-Tissue_2 [RNA-Seq] GSM2653831 CC2-Tissue [RNA-Seq] GSM2653832 CC3-Tissue [RNA-Seq]

肯定是不能一个个手动点击样本信息进入寻找文件下载链接，那样低效。

查看具体的每个文件

压缩包解压的方式下载表达矩阵后，发现，每个样本都是一个文本文件：

GSM2653819_Counts_notmergedTR_Healthy1_Tissue_1.txt.gz GSM2653820_Counts_notmergedTR_Healthy1_Tissue_2.txt.gz GSM2653821_Counts_notmergedTR_Healthy2_Tissue.txt.gz GSM2653822_Counts_notmergedTR_Healthy3_Tissue.txt.gz GSM2653823_Counts_notmergedTR_HCC1_Tissue_1.txt.gz GSM2653824_Counts_notmergedTR_HCC1_Tissue_2.txt.gz GSM2653825_Counts_notmergedTR_HCC3_Tissue.txt.gz GSM2653826_Counts_notmergedTR_CHC1_Tissue_1.txt.gz GSM2653827_Counts_notmergedTR_CHC1_Tissue_2.txt.gz GSM2653828_Counts_notmergedTR_CHC2_Tissue.txt.gz GSM2653829_Counts_notmergedTR_CC1_Tissue_1.txt.gz GSM2653830_Counts_notmergedTR_CC1_Tissue_2.txt.gz GSM2653831_Counts_notmergedTR_CC2_Tissue.txt.gz GSM2653832_Counts_notmergedTR_CC3_Tissue.txt.gz GSM2653833_Counts_notmergedTR_Healthy1_Organoid_1.txt.gz GSM2653834_Counts_notmergedTR_Healthy1_Organoid_2.txt.gz GSM2653835_Counts_notmergedTR_Healthy2_Organoid.txt.gz GSM2653836_Counts_notmergedTR_Heal

【本文地址】

公司简介

联系我们