DVL2 dishevelled segment polarity protein 2 [Homo sapiens (human)]

2024-07-10 05:04| 来源: 网络整理| 查看: 265

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_033038.1 RefSeqGene

Range 5028..14203 Download GenBank, FASTA, Sequence Viewer (Graphics) mRNA and Protein(s)

NM_004422.3 → NP_004413.1 segment polarity protein dishevelled homolog DVL-2

See identical proteins and their annotated locations for NP_004413.1

Status: REVIEWED

Source sequence(s) AK026019, BC014844, BG716400, CB994349 Consensus CDS CCDS11091.1 UniProtKB/Swiss-Prot D3DTN3, O14641, Q53XM0 UniProtKB/TrEMBL I3L2N2 Related ENSP00000005340.4, ENST00000005340.10 Conserved Domains (5) summary smart00021Location:13 → 93 DAX; Domain present in Dishevelled and axin cd00992Location:265 → 352 PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ... cd04438Location:424 → 507 DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ... pfam02377Location:125 → 263 Dishevelled; Dishevelled specific domain pfam12316Location:515 → 726 Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCh38.p14 Primary Assembly Genomic

NC_000017.11 Reference GRCh38.p14 Primary Assembly

Range 7225342..7234517 complement Download GenBank, FASTA, Sequence Viewer (Graphics) mRNA and Protein(s)

XM_005256502.3 → XP_005256559.1 segment polarity protein dishevelled homolog DVL-2 isoform X1

UniProtKB/TrEMBL I3L2N2 Conserved Domains (5) summary smart00021Location:13 → 93 DAX; Domain present in Dishevelled and axin cd00992Location:261 → 348 PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ... cd04438Location:420 → 503 DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ... pfam02377Location:125 → 259 Dishevelled; Dishevelled specific domain pfam12316Location:511 → 722 Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

XM_047435518.1 → XP_047291474.1 segment polarity protein dishevelled homolog DVL-2 isoform X2

UniProtKB/TrEMBL I3L2N2

XM_047435522.1 → XP_047291478.1 segment polarity protein dishevelled homolog DVL-2 isoform X5

XM_047435520.1 → XP_047291476.1 segment polarity protein dishevelled homolog DVL-2 isoform X4

XM_047435519.1 → XP_047291475.1 segment polarity protein dishevelled homolog DVL-2 isoform X3

Alternate T2T-CHM13v2.0 Genomic

NC_060941.1 Alternate T2T-CHM13v2.0

Range 7126253..7135444 complement Download GenBank, FASTA, Sequence Viewer (Graphics) mRNA and Protein(s)

XM_054315308.1 → XP_054171283.1 segment polarity protein dishevelled homolog DVL-2 isoform X1

UniProtKB/TrEMBL I3L2N2

XM_054315309.1 → XP_054171284.1 segment polarity protein dishevelled homolog DVL-2 isoform X2

UniProtKB/TrEMBL I3L2N2

XM_054315312.1 → XP_054171287.1 segment polarity protein dishevelled homolog DVL-2 isoform X5

XM_054315311.1 → XP_054171286.1 segment polarity protein dishevelled homolog DVL-2 isoform X4

XM_054315310.1 → XP_054171285.1 segment polarity protein dishevelled homolog DVL-2 isoform X3

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