CCL2 分子靶点信息 |
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人 Human CCL2 分子靶点信息
分子名:CCL2, C-C motif chemokine ligand 2
别称:
C-C motif chemokine 2
chemokine (C-C motif) ligand 2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
MGC9434
monocyte chemoattractant protein 1
monocyte chemoattractant protein-1
monocyte chemotactic and activating factor
monocyte chemotactic protein 1
monocyte secretory protein JE
SCYA2
small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
small inducible cytokine subfamily A (Cys-Cys), member 2
small-inducible cytokine A2
SMC-CF
基因序列:NCBI_Gene: 6347
蛋白序列:UniProtKB: P13500
人 Human CCL2靶点分子功能(预测)
Predicted to enable CCR2 chemokine receptor binding activity and chemokine activity. Involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and regulation of apoptotic process. Located in extracellular region. Implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and tuberculosis (multiple). Biomarker of several diseases, including autoimmune disease (multiple); liver disease (multiple); lung disease (multiple); non-alcoholic fatty liver disease (multiple); and retinal disease (multiple). 小鼠 Mouse Ccl2 分子靶点信息 分子名:Ccl2, chemokine (C-C motif) ligand 2 别称: AI323594 expressed sequence AI323594 HC11 MCAF MCP-1 MCP1 monocyte chemoattractant protein-1 monocyte chemotactic protein Scya2 Sigje small inducible cytokine A2 small inducible gene JE SMC-CF 基因序列:NCBI_Gene: 20296 蛋白序列: UniprotKB: P10148 UniprotKB: Q3U5L6 UniprotKB: Q3U5S8 UniprotKB: Q5SVU3 UniprotKB: Q7TMS1 小鼠 Mouse Ccl2 靶点分子功能(预测)Enables CCR2 chemokine receptor binding activity and cytokine activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of leukocyte chemotaxis; and positive regulation of macromolecule metabolic process. Acts upstream of or within response to bacterium and response to wounding. Located in extracellular space. Is expressed in several structures, including heart; intestine smooth muscle circular layer; nervous system; retina; and vibrissa. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and tuberculosis (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2). 大鼠 Rat Ccl2 分子靶点信息 分子名:Ccl2, C-C motif chemokine ligand 2 别称: C-C motif chemokine 2 chemokine (C-C motif) ligand 2 immediate-early serum-responsive JE protein immediate-early serum-responsive protein JE MCP-1 monocyte chemoattractant protein 1 monocyte chemoattractant protein-1 monocyte chemotactic protein 1 Scya2 Sigje small inducible cytokine A2 Small inducible gene JE small-inducible cytokine A2 基因序列:NCBI_Gene: 24770 蛋白序列:UniProtKB: P14844 大鼠 Rat Ccl2 靶点分子功能(预测)Enables chemokine activity and heparin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and leukocyte migration. Located in several cellular components, including perikaryon; perinuclear region of cytoplasm; and rough endoplasmic reticulum. Colocalizes with C-fiber. Used to study several diseases, including artery disease (multiple); diabetic angiopathy; interstitial lung disease (multiple); kidney disease (multiple); and pancreatitis (multiple). Biomarker of several diseases, including artery disease (multiple); cerebrovascular disease (multiple); lung disease (multiple); non-alcoholic fatty liver disease (multiple); and pancreatitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and tuberculosis (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2). |
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