不饱和烃的电子驱动硝化,Angewandte Chemie International Edition

Herein, we present a concept for the generation of nitryl radicals from ferric nitrate that is driven by substoichiometric amounts of electrons, introduced electrochemically. This protocol enables access to a variety of nitro-derived molecules from unsaturated hydrocarbons including alkenes, alkynes, and arenes, in addition to promoting ipso-nitration reactions and nitrative cyclizations with high levels of chemo- and regioselectivity.