李爽

李爽 博士 助理研究员

山东大学国家糖工程技术研究中心

邮箱：[email protected]

电话：0532-58631412

教育经历

2016.9-2021.6     山东大学，国家糖工程技术研究中心，理学博士

2012.9-2016.6     南京理工大学，化工学院，理学学士

工作经历

2023.12-至今  山东大学，国家糖工程技术研究中心助理研究员

2021.7-2023.11 山东大学，国家糖工程技术研究中心，博士后

研究方向

主要围绕均一寡多糖的制备及其生物学功能开展研究工作，具体包括：

1）糖胺聚糖合成酶及降解酶的筛选及应用

2）透明质酸蛋白质组学研究

科研项目

1) 山东省自然科学基金青年项目， 2023.1-2025.12，主持

2）中国博士后基金面上项目，2023.1-2024.12，主持

代表性论著

1. Shuang Li#, Shuaishuai Wang#, Jingyao Qu, Jingjun Han, Lin Yang, Yi Li, Qingwen Jia, Congcong Chen, Peixue Ling and Junqiang Fang, Programmable One Cycle-One Disaccharide Unit Modular Synthesis of Hyaluronan and Chondroitin Hybrid Glycans. Green Chemistry. 2023.

2. Lin Yang, Shuaishuai Wang, Changshen Chen, .Changcheng Liu, Xiaoqin Wang, Shuang Li, Yi Li, Peixuye Ling, Zhongfu Wang and. Junqiang Fang, Programmable Enzymatic Toolbox for the Assembly of Fucosylated Chondroitin Derivatives. Acs Catalysis. 2023.

Peng Zhang, Lijuan Zhang, Xukai Jiang, Xiao-tong Diao, Shuang Li, Dan-dan Li, Zheng Zhang,

Junqiang Fang, Ya-jie Tang, Da-lei Wu , Changsheng Wu and Yue-zhong Li, Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B. Communications Biology. 2022.

3. Shuang Li#, Shuaishuai Wang#, Yaqian Wang, Jingyao Qu, Xian-wei Liu, Peng George Wang, and Junqiang Fang. 2021. Gram-scale production of sugar nucleotides and their derivatives. Green Chemistry. 2021.

4. Shuang Li, Shuaishuai Wang, Xuan Fu, Xian-wei Liu, Peng George Wang, Junqiang Fang*. 2017. Sequential One-pot Multienzyme Synthesis of Hyaluronan and its Derivative. Carbohydrate Polymers. 2017.

5. 房俊强，李爽，王鹏，一种糖核苷酸及其衍生物的制备方法。（专利，ZL202010663150.6）

6. Yaqian Wang, Shuang Li, Xuan Xu, Yujie Tan, Xian-wei Liu, Junqiang Fang. Chemoenzymatic synthesis of homogeneous chondroitin polymers and its derivatives. Carbohydrate Polymers. 2020.

7. Lin Yang, Xuan Xu, Shuang Li, Yi Li, Peixue Ling, Junqiang Fang, Robust one-pot multienzyme polysaccharide remodeling strategy for the synthesis of uniform chondroitin fragments and derivatives, Carbohydrate Research.2021.