富血小板血浆治疗慢性半月板损伤的前期疗效观察

To observe the clinical efficacy of platelet rich plasma (PRP) injection in the treatment of chronic meniscus injury.

From January 2016 to October 2017, a total of 35 patients with chronic meniscus injury, which courses were more than 6 months, were treated with PRP injection in Shaoguan Hospital Affiliated to Southern Medical University. Their knee joints were immobilized for three weeks after the first injection and followed up for three to six months. Lysholm score, visual analogue pain score (VAS), meniscus rotation test (McMurray test), Stoller injury grading of MR images were used to evaluate the efficacy. The incidence of complications was also observed. Lysholm score and visual analogue pain score (VAS) were analyzed by variance analysis of repeated measurements. The counting data of McMurray test and MRI image were analyzed by chi-square test.

There were 35 patients with 37 knees and 47 meniscuses, aged from 24 to 71 years, (56±13)years on average. Course of disease were six to 112 months, average (48±33) months. The Lysholm knee score was (65.1±4.8), (68.8±5.1), (71.6±4.8), (72.5±4.9)respectively before treatment, and one month, two months, three months after the first injection; the difference was statistically significant(F=1 968.5, P