王琰

1. Xiao‑Yang Li, Zhen‑Xiong Zhao, Min Huang, Ru Feng, Chi‑Yu He, Chao Ma, Shi‑Heng Luo, Jie Fu, Bao‑Ying Wen, Long Ren, Jia‑Wen Shou, Fang Guo, Yangchao Chen, Xin Gao, Yan Wang*, Jian‑Dong Jiang*. Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters. Journal of Translational Medicine, 2015, 13(1): 278. 2. Hong-Mei Yan , Ming-Feng Xia, Yan Wang, Xin-Xia Chang, Xiu-Zhong Yao, Sheng-Xiang Rao, Meng-Su Zeng, Yin-Fang Tu, Ru Feng, Wei-Ping Jia, Jun Liu, Wei Deng, Jian-Dong Jiang*, Xin Gao*. Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease. PLoS One, 2015, 10 (8): e0134172. DOI: 10.1371/journal.pone. 0134172. 3. Ru Feng, Jia-Wen Shou, Zhen-Xiong Zhao, Chi-Yu He, Chao Ma, Min Huang, Jie Fu, Xiang-Shan Tan, Xiao-Yang Li, Bao-Ying Wen, Xi Chen, Xin-Yi Yang, Gang Ren, Yuan Lin, Yangchao Chen, Xue-Fu You, Yan Wang*, Jian-Dong Jiang*. Transforming berberine into its intestine absorbable form by gut microbiota. Scientific Reports, 2015, 5: 12155. 4. Yan Wang*, Jia-Wen Shou, Jian-Dong Jiang*. Metabolism of Chinese Materia Medica in gut microbiota and biological effects. Chinese Herbal Medicines, 2015, 7(2): 109-115. 5. Bao-Hui Cheng, Xuelin Zhou, Yan Wang, Judy Yuet-Wa Chan, Huang-Quan Lina, Penelope M.Y. Or, David Chi-Cheong Wan, Ping-Chung Leung, Kwok-Pui Funga, Yi-Fen Wang*, Clara Bik-San Laua*. Herb-drug interaction between an anti-HIV Chinese herbal SH formula and Atazanavir in vitro and in vivo. Journal of Ethnopharmacology, 2015, 162(13): 369-376. 6. Zhangang Xiao, Chi Han Li, Stephen L. Chan, Feiyue Xu, Lu Feng, Yan Wang, Jian-Dong Jiang, Joseph JY Sung, Christopher HK Cheng, and Yangchao Chen*. A small-molecule modulator of the tumor-suppressor mir34a inhibits the growth of hepatocellular carcinoma. Cancer Research, 2014, 74(21): 6236-6247. 7. Chi-Yu He, Jie Fu, Jing-Yi Ma, Ru Feng, Xiang-Shan Tan, Min Huang, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Xian-Feng Zhang*, Yangchao Chen* and Yan Wang*. Biotransformation and in vitro metabolic profile of bioactive extracts from a traditional miao-nationality herbal medicine, Polygonum capitatum. Molecules, 2014, 19: 10291-10308. 8. Jing-Yi Ma, Xuelin Zhou, Jie Fu, Tao Hu, Penelope M.Y. Or, Ru Feng, Chi-Yu He, Wen-Jing Chen, Xian-Feng Zhang*, Yangchao Chen**, Yan Wang***, John H.K. Yeung. Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro. Chemico-Biological Interactions, 2014, 220: 33-40. 9. Ming Zhao*, Xianming Zhang, Yan Wang*, Min Huang, Jin-Ao Duan, Tanja Gödecke, Karina M. Szymulanska-Ramamurthy, Zhiqi Yin, Chun-Tao Che. Germacranes and m-Menthane from Illicium lanceolatum. Molecules, 2014, 19(4): 4326-4337. 10. Ru Feng, Xuelin Zhou, Xiang-Shan Tan, Penelope M.Y. Or, Tao Hu, Jie Fu, Jing-Yi Ma, Min Huang, Chi-Yu He, Jian-Gong Shi, Chun-Tao Che, John H.K. Yeung*, Yan Wang*. In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2, 3, 5-trimethoxy-xanthone purified from Halenia elliptica D. Don. Chemico-Biological Interactions, 2014, 210: 12-19. 11. Yan Wang, Jing-Yi Ma, SC Chow, Chi-Han Li, Zhangang Xiao, Ru Feng, Jie Fu, Yangchao Chen*. A potential antitumor ellagitannin, davidiin, inhibited hepatocellular tumor growth by targeting EZH2. Tumor Biology, 2014, 35 (1): 205-212. 12. Xiang-Shan Tan, Jing-Yi Ma, Ru Feng, Chao Ma, Wen-Jing Chen, Yu-Peng Sun, Jie Fu, Min Huang, Chi-Yu He, Jia-Wen Shou, Wen-Yi He, Yan Wang*, Jian-Dong Jiang*. Tissue distribution of Berberine and its metabolites after oral administration in rats. PLoS One, 2013, 8(10): e77969. doi:10.1371/journal.pone.0077969. 13. Jing-Yi Ma, Ru Feng, Xiang-Shan Tan, Chao Ma, Jia-Wen Shou, Jie Fu, Min Huang, Chi-Yu He, Shuo-Nan Chen, Zhen-Xiong Zhao, Wen-Yi He, Yan Wang*, Jian-Dong Jiang**. Excretion of berberine and its metabolites in oral administration in rats. Journal of Pharmaceutical Sciences, 2013, 102(11): 4181-4192. 14. Ming-Na Sun, Jin-Feng Hu, Xiu-Yun Song, Dong-Hui Wu, Ling-Lei Kong, Yu-Peng Sun, Dong-Mei Wang, Yan Wang**, Nai-Hong Chen***, Gang Liu*. Coumarin derivatives protect against ischemic brain injury in rats. European Journal of Medicinal Chemistry, 2013, 67: 39-53. 15. Min Huang, Wen-Jing Chen, Ying Zhou, Ru Feng, Jie Fu, Jing-Yi Ma, Xiang-Shan Tan, Chi-Yu He ,Qi-Ming Zhang, Wen-Yi He, Yu-Lin Deng, Yu-Kui Zhang, Xian-Feng Zhang, Yan Wang*. Enantiomeric separations of four basic drugs containing N-alkyl groups by a RP-HPLC system using SBE-β-CD as chiral mobile phase additive. Chinese Chemical Letters, 2013, 24 (9): 840-844. 16. Yan Wang**, Ying Zhou, Chao Ma, Bei-Bei Yang, Ru Feng, Yi-Ying Zhang, Jie Fu, Wen-Jing Chen, Yu-Peng Sun, Jing-Yi Ma, Qi-Ming Zhang, Yu-Lin Deng, Yu-Kui Zhang, Wen-Yi He. High performance liquid chromatographic separation of eight drugs collected in Chinese Pharmacopoeia 2010 on amylose ramification chiral stationary phase. Acta Pharmaceutica Sinica B, 2012, 2 (5): 527-533. 17. Jie Fu, Jing-Yi Ma, Xian-Feng Zhang, Yan Wang**, Ru Feng, Yang-Chao Chen, Xiang-Shan Tan, Yi-Ying Zhang, Yu-Peng Sun, Ying Zhou, Chao Ma, Chi-Yu He, Zhen-Xiong Zhao, Xiao-Wei Du. Identification of metabolites of FR429, a potential antitumor ellagitannin, transformed by rat intestinal bacteria in vitro, based on liquid chromatography–ion trap-time of flight mass spectrometry analysis. Journal of Pharmaceutical and Biomedical Analysis, 2012, 71: 162-167. 18. Ru Feng, Xuelin Zhou, Penelope M.Y. Or, Jing-Yi Ma, Xiang-Shan Tan, Jie Fu, Chao Ma , Jian-Gong Shi, Chun-Tao Che, Yan Wang**, John H.K. Yeung*. Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes. Phytomedicine, 2012, 19: 1125-1133. 19. Ru Feng, Yi-Ying Zhang, Xi Chen, Yan Wang**, Jian-Gong Shi, Chun-Tao Che, John H.K. Yeung, Jing-Yi Ma, Xiang-Shan Tan, Chen Yang, Yu-Lin Deng, Yu-Kui Zhang. In vitro study on metabolite profiles of bioactive xanthones isolated from Halenia elliptica D. Don by high performance liquid chromatography coupled to ion trap time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2012, 62: 228–234. 20. Ying Zhou, Chao Ma, Yan Wang**, Qi-Ming Zhang, Yi-Ying Zhang, Jie Fu, Hong Gao, Li-Xun Zhao. High performance liquid chromatographic separation of thirteen drugs collected in Chinese Pharmacopoeia 2010 (Ch.P2010) on cellulose ramification chiral stationary phase. Journal of Pharmaceutical Analysis, 2012, 2: 48-55.